Vizcaya is connected by means of one of the best motorway networks (toll and free) in the whole country, and Bilbao is the communications hub for the north of the Iberian Peninsula.

The AP-8 motorway goes to Donostia/San Sebastián and Irún, and from there continues on to Bordeaux and Paris, or Toulouse and Montpellier. The AP-68, which runs through the Ebro Valley, goes to Barcelona and joins the AP-7, which runs down the Mediterranean coast. The AP-68 also goes straight to Burgos, and from there to Madrid, Valladolid and Portugal.

From the Termibus bus station, located in the heart of the city centre, there are many different bus companies that provide regional, national and international services.

Situated some 12 kilometres outside the city centre, the international airport of Bilbao is considered the air transport hub of the north of the peninsula, and is connected to the main cities in the country, as well as to all major European destinations. The airport is linked to the city by bus number A3247, which runs from the Termibus station and stops at the Plaza Moyúa square, at Gran Vía 79 and at Alameda Rekalde 11. It runs between 6:15 am and midnight towards Bilbao, and between 5:20 am and 10 pm to the airport.

From the ferry depot at Santurtzi port, ferries travel to the English port of Portsmouth and back twice a week, with the option of taking your car with you. The port can be reached by city bus from Plaza Jado square on the C-1 suburban train line and by road on the AP-8 motorway.

Finally, inter-city RENFE trains depart from the Bilbao-Abando station daily to Madrid and Barcelona, and have direct connections to regions such as Castile-León, La Rioja and Aragon.